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(Hereinafter referred to as R-1881 (or RU-1881), NSC-92858), also known as methylenetrienol (or 17-methylprednisolone),and17-methyl-19- Dihydroxy-4,9,11-trien-17β-alcohol-3-one is an efficient, orally active, non-aromatic, synthetic and metabolic androgen Steroids (AAS)  Nasal testosterone and 17α-alkylated groups, which have never been clinically marketed, have been used in scientific studies as a combination of androgen receptor (AR) and AR ligand binding assays Affinity mark. It is a 17α-methylated derivative of trienolone, which is similar to AAS, but is similar to other 17α-alkylated AASs with high hepatotoxic potential. Metribolone binds not only to AR but also to progesterone receptor (PR) and binds to glucocorticoid receptor (GR). It is said that this is the most powerful AAS.
Eleven members of the Greek national weightlifting team and four Greek track and field athletes tested methotrienols before the 2008 Beijing Olympic Games.
Metribolone (methylenetriol Aka R1881) is a potent, non-aromatic androgen that is structurally similar to talbolone and is called "oral trend". Methotrienol is strongly bound to the androgen receptor (AR), which is more effective for agonists (activators) than the androgen receptor DHT. According to Julius Vida in the "Androgen and Synthetic Metabolism: Chemistry and Pharmacology" listed in the proportion of synthetic metabolites up to 30,000 times the methyl testosterone. The effective dose starts at 25 mcg only.
Steroids experts William Llewellyn and Patrick Arnold all call methyltrienol is one of the "most powerful" metabolic steroids ever created. It is also one of the most toxic androgens of all time. Initially developed by Roussell-UCLAF in the 1960s, Metribolone's hepatotoxicity prevented its commercial release. Bill Roberts compares methotrienol toxicity while taking high doses of annar combined with high doses of oseltamycin.
According to Patrick Arnold, dozens of athletes use methylenetrienol in the 1990s, and because of the small number of steroids that require increased performance, they can successfully find methyl groups through stimulants Trienol. He was surprised that in the Greek sterile scandal, the drug testers detected methotrienol, indicating an improvement in the anti-doping test of the substance; 11 Greek weighing athletes and four Greek athletes in 2008 Before the Beijing Olympic Games, the methotrienols were tested.
Patrick Arnold is an organic chemist and has developed an undetectable synthetic metabolic steroid tetrahydropregnenone (THG) for BALCO. THG is a modified form of methyltrienol. In March 1997, Patrick Arnold published a detailed formula on how to synthesize methyltrienol from an easy-to-obtain veterinarian Finaplix-H (octophorone acetate) pills.
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