Oral Contraceptive Female Steroids Megestrol Acetate Horrmone Powder CAS:595-33-5 for Treat Dysmenorrhea

Oral Contraceptive Female Steroids Megestrol Acetate Horrmone Powder CAS:595-33-5 for Treat Dysmenorrhea

99% Megestrol Acetate powder E-mail: claire@chembj.com Skype: live:695059711 whats app: +8615527046746 Quick detail Megestrol acetate Product name: Megestrol acetate CAS Registry Number: 595-33-5 Assay: 99% Molecular Formula: C24H32O4 Molecular weight: 384.52 Reference Standards: BP2003;USP29;...

Product Details

99% Megestrol Acetate powder E-mail: claire@chembj.com

Skype: live:695059711 whats app: +8618123714275

Quick detail

Megestrol acetate
Product name: Megestrol acetate
CAS Registry Number: 595-33-5
Assay: 99%
Molecular Formula: C24H32O4
Molecular weight: 384.52
Reference Standards: BP2003;USP29; EP5.0
Appearance: White or slightly yellow crystalline powder

Description

Megestrol acetate has powerful antiandrogenic and antiestrogenic effects in humans at sufficient doses, capable of decreasing circulating androgen and estrogen concentrations to castrate levels in both sexes and significantly lowering the expression of the androgen receptor (AR) and the estrogen receptor (ER) in the body.
As an example, one study in men with benign prostatic hyperplasia who were treated with 120-160 mg of megestrol acetate per day for 3 to 11 days found average decreases in AR quantity of 73% and 86% in the cytoplasm and nucleus of prostatic cells.

These actions are likely the result of a strong activation of the PR, which suppresses the secretion of the gonadotropins-peptide hormones responsible for signaling the body to produce not only progesterone but also the androgens and the estrogens-from the pituitary gland as a form of negative feedback inhibition.
And hence downregulates the hypothalamic-pituitary-gonadal (HPG) axis, resulting in decreased levels of the sex hormones and their associated enzymes, carriers (e.g., sex hormone-binding globulin), and receptors.
It is the antiandrogenic and antiestrogenic effects of megestrol acetate mediated by suppression of the HPG axis that are believed to be largely responsible for its beneficial effects against androgen and estrogen-sensitive cancers, respectively.

Usage
Mainly used for short-acting oral contraceptives, can also be used for intramuscular injection of long-acting contraceptives.

For the treatment of dysmenorrhea, amenorrhea, dysfunction of uterine bleeding, endometriosis and endometrial adenocarcinoma.

Medroxyprogesterone acetate is mainly used as an appetite stimulant under various conditions and is used as an antitumor agent for the treatment of breast cancer, endometrial cancer and prostate cancer.

When administered at a fairly high dose, it can significantly increase the appetite of individuals in most individuals and even those with advanced cancer and is commonly used to increase appetite and induce weight gain in patients with cancer or HIV / AIDS associated cachexia The It is also used as a contraceptive in combination with lower doses of estrogen.

In addition to the use in the human body, methylprednisolone acetate is widely used in veterinary treatment of cats and dogs in the medical condition.


FAQ

Q1:Have your product quality been approved by Third Party Lab?

A:Yes,All products are strictly tested by our QC,confirmed by QA and approved by third party lab in China,USA,Canada,Germany,UK,Italy,France etc.So you will be assured with Good Quality if you choose us.

Q2:How do you treat quality complaint?

A:First of all,our QC department will do strict examination of our export products by HPLC,UV,GC,TLC and so on in order to reduce the quality problem to near zero.If there is a real quality problem,caused by us,we will send you free goods for replacement or refund your loss.

Q3:Do you accept sample order?

A:Yes,we accept small order from 10g,100g and 1kg for your evaluation quality of our goods.

Q4:Is there any discount?

A:Yes,for larger quantity,we always support with better price.

Q5:How long does it take to arrive?

A:It is Depending on your location,

For small order,please expect 5-7 days by DHL,UPS,TNT,FEDEX,EMS.

For mass order,please allow 5-8 days by Air,20-35 days by Sea.

Q6:Do you have any reshipment policy?

Yes we will reship for totally free if your parcles is seizd by customs unlucky,you dont need to pay any more money

Q7:what payment do you offer?

TT(bank transfer),west union,money gram,bitcoin

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E-mail:claire@chembj.com

Skype:live:695059711

Whatapp:+8618123714275

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