Estradiol Benzoate EB Powder Pharmaceutical Raw Materials Antiacne Antineoplastic CAS 50-50-0

Estradiol Benzoate EB Powder Pharmaceutical Raw Materials Antiacne Antineoplastic CAS 50-50-0

Estradiol Benzoate EB Powder Pharmaceutical Raw Materials Antiacne Antineoplastic CAS 50-50-0 Whatsapp:+8618126147481 Skype:cherrysendi Emial:cherrysendi@chembj.com Estradiol benzoate Assay:99.09% Product name: Estradiol benzoateCAS No.: 50-50-0M.F.: C25H28O3M.W.: 376.49 Assays: 99.09% Packing:...

Product Details

Estradiol Benzoate EB Powder Pharmaceutical Raw Materials Antiacne Antineoplastic CAS 50-50-0

Whatsapp:+8618126147481

Skype:cherrysendi

Emial:cherrysendi@chembj.com


Estradiol benzoate
Assay:99.09%
Product name: Estradiol benzoateCAS
No.: 50-50-0M.F.: C25H28O3M.W.: 376.49
Assays: 99.09%
Packing: 5kg/tin
Quality standards: EP5.0
Appearance: Almost white crystalline powder or colourless crystals


What is Estradiol benzoate

Estradiol benzoate (INN; brand names Agofollin, Diffolisterol,Progynon-B, many others), or oestradiol benzoate (BAN), is a syntheticester, specifically the 3-benzoyl ester, of the natural estrogen,estradiol. It was the first form of estrogen to be marketed, patented by Schering-Kahlbaun in 1936 in an oil preparation for injectable use and introduced later that year as Progynon-B. Though it is still in widespread use today, it has been mostly superseded by newer forms of estradiol with improved pharmacokinetics in which require less frequent administration such as estradiol cypionate and estradiol valerate.


Estradiol benzoate benefits

Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor, and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol.


Estradiol benzoate COA

Product name

Estradiol Benzoate

Appearance

White crystalline powder

Water

≤3.5%

pass

Assay

97 .0~ 103.0%

99.2%

Loss on drying

≤0.5%

0.17%

Related substances

total impurities ≤1.0%

Pass

any individual impurity ≤0.5%

Pass


Residual solvents

ethanol ≤0.5%

Pass


Estradiol benzoate effects

The effects of daily injections of 5 microgram estradiol benzoate (EB) on the patterns of food and ethanol consumption were studied in ovarectomized rats given free access to food, a 10% ethanol solution, and water. EB led to an immediate, but transient, suppression of both food and ethanol intake. The time course and magnitude of these effects were virtually identical. While the decrease in total food intake was achieved by a permanent decrease in the duration of eating bouts, the decline in total ethanol consumption apparently resulted from decreased rates of licking within bouts. Gradual increases in the frequency of eating and ethanol-drinking bouts allowed total food and ethanol intake to return to baseline within three weeks of the first injection. Total water intake rose three-fold during EB administration and this was due to increases in both the duration and frequency of drinking bouts. The similarity in effects induced by EB on the patterns of food and ethanol intake were discussed in terms of ethanol's caloric property.


1.Our Service

7*24 hours service by emial,whatsapp,skype

others customers tracking numbers

Offer product COA;and samples for test

2.Quality

1.Having been engaged in this field for years,before export,we are top maunfacture of steroid in China market more than ten years.

2.Most products are 99%+ pure and EP/USP standard.

3.Payment

we are accpet Western union,Bank transfer, Bitcion,Money gram,Alipay


Packing&shipping

1.Packages are generally dispatched within 24 hours after payment

2.After shipping we will provide: tracking number;pictures with your parcel;

3.Shipping Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.

4.Air transport for large quantity

5.Shipping time:Most countries can arrived within 3-10 days door to door


More information please feel free conatct me

Whatsapp:+8618126147481

Skype:cherrysendi

Emial:cherrysendi@chembj.com

Inquiry