99% Purity Female Hormone Estrogen Altrenogest powder Steroids CAS850-52-2
CAS No.: 850-52-2
Molecular Weight: 310.47
Density: 1.15 g/cm3
Boiling Point: 495.6 C at 760 mmHg
Flash Point: 210.1Storage: store in cool, dry, ventilated place
PackAge: Foil Bag or According to Your Requirements.
Application :Pharmaceutical and biochemical research,animal conception control
Grade: Pharma Grade
Appearance: light yellow crystal or powder
Progestins are primarily produced endogenously by the corpus luteum.They transform proliferative endometrium to secretory endometrium,enhance myometrium hypertrophy and inhibit spontaneous uterine contraction.Progestins have a dose-dependent inhibitory effect on the secretion of pituitary gonadotropins and also have some degree of estrogenic, anabolic and androgenic activity.
The pharmacodynamic activity of altrenogest has been demonstrated in a number of animal models.The most important effects are the progestomimetic and anti-gonadotrophic effects.Altrenogest also has weak oestrogenic,anabolic and androgenic effects,but has no corticoid or anti-inflammatory effects.
Altrenogest is effective in normally cycling mares for minimizing the necessity for estrus detection, for the synchronization of estrus and permitting scheduled breeding. Estrus will ensue 2-5 days after treatment is completed and most mares ovulate between 8-15 days after withdrawal. Altrenogest is also effective in suppressing estrus expression in show mares or mares to be raced. Although the drug is labeled as contraindicated during pregnancy, it has been demonstrated to maintain pregnancy in oophorectomized mares and may be of benefit in mares who abort due to sub-therapeutic progestin levels.
In veterinary medicine, altrenogest is used in gilts and mares for zootechnical purposes (oestrus synchronization). The recommended dose for gilts is 20 mg/animal/day given orally for 18 consecutive days, and for mares is 0.044 mg/kg bw/day given orally for 10 to 15 days.
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