Effective Anti Estrongen Steriods Toremifene Citrate Powder CAS89778-27-8

Effective Anti Estrongen Steriods Toremifene Citrate Powder CAS89778-27-8

Effective Anti Estrongen Steriods Toremifene Citrate powder CAS89778-27-8 Whatsapp:+8618126147481 Skype:cherrysendi Emial:cherrysendi@chembj.com Toremifene Citrate Toremifene Citrate COA Toremifene Citrate application Toremifene citrate is an oral selective estrogen receptor modulator (SERM)...

Product Details

Effective Anti Estrongen SteriodsToremifene Citrate powder CAS89778-27-8

Whatsapp:+8618126147481

Skype:cherrysendi

Emial:cherrysendi@chembj.com

Toremifene Citrate

Product Name

Toremifene Citrate

Chemical Name

Fareston

CAS Number

89778-27-8

Molecular Formula

C26H28ClNO

Molecular Weight

598.09

Melting Point

160-162℃

Assay

99.5%

Appearance

White powder

Toremifene Citrate COA

Description

White or Almost White Crystalline Powder

white powder

Identification

A.B.

Positive

Assay

97.0~103.0%

99.0%

Specific Rotation

+101°~+105°

+102.6°

Loss On Drying

1.0%max

0.28%

Organic Volatile Impurities

meets the requirement.

Conforms

Related Substances

meets the requirement.

Conforms

Residual Solvents

meets the requirement.

Conforms

Particle Size

100% ≤ 20 microns

Conforms

Toremifene Citrate application

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.


It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels

Toremifene Citrate dosage

In the fight against breast cancer, standard Fareston doses will normally be 60mg per day. The total duration of use is unpredictable and will be based on patient need. It's not uncommon for treatment to last a year or two and then AI's to be added if needed. Once the cancer is in remission, compounds like Fareston are commonly used to support the improved state.

Toremifene Citrate effects

does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.

is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.

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