Clomiphene Citrate Clomifene Citrate 50-41-9 for Female Infertility Treatment

Clomiphene Citrate Clomifene Citrate 50-41-9 for Female Infertility Treatment

Quick Detail Product Description Introduction Clamiphene, also known as clomiphene, is a drug for the treatment of infertility among women who do not ovulate. This includes those who have polycystic ovary syndrome. Use the results to have greater twin opportunities. Oral is once a day. Common...

Product Details

Quick Detail

Product Name

Clomiphene Citrate

CAS NO

50-41-9

Assay

99% above

Molecular Weight

598.083

Density

N/A

Boiling Point

509ºC at 760 mmHg

Molecular Formula

C32H36ClNO8

Melting Point

116.5-118°C

Flash Point

261.6ºC

Appearance

White Powder

Packaging

1kg foil bag

Price

882-1323USD/KG

MOQ

1kg

Sample

Availability

Origin China

China

Payment Term

TT/West Union/Money Gram/Bitcoin

Delivery Time

3-5 working days by express normally

Product Description

Introduction

Clamiphene, also known as clomiphene, is a drug for the treatment of infertility among women who do not ovulate. This includes those who have polycystic ovary syndrome. Use the results to have greater twin opportunities. Oral is once a day.

Common side effects include pelvic pain and hot flushing. Other side effects may include visual changes, vomiting, sleep disorders, ovarian cancer and seizures. Do not recommend people with liver disease or pregnancy. Clomiphene is in the selective estrogen receptor modulator (SERM) series of drugs. Its role is through the hypothalamus release of gonadotropin.

Clomifene was approved for medical use in the United States in 1967. It is the most effective and safe drug in the health system on the list of essential medicines on the World Health Organization. It can be used as a generic drug. The wholesale costs for developing countries ranged from $ 0.79 to $ 2.00. In the United States, the cost of a course of treatment is $ 4.80. Its introduction began the era of assisted reproductive technology.

Structure

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Spectrum


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Applications

Cramiphene can be used for infertile people due to ovulation or low ovulation. In the absence of known reasons, there is insufficient evidence for the use of clomiphene in infertile patients. In this case, the study has observed that clomiphene treatment of clinical pregnancy rate of 5.6% per cycle, while untreated for each cycle 1.3% -4.2%.

Clamiphene is also used in other assisted reproductive techniques to improve the success rate of these other methods.

The correct time for the drug is important; it should start on the fifth day of the cycle and should be frequent.

The following procedure can be used to monitor the induction period:

Tandem transvaginal ultrasound can show the size and number of follicles in development. It can also provide evidence of ovulation hypothesis, such as sudden collapse of follicles before ovulation, and an increase in the volume of liquid in the rectum sacks. After ovulation, it may show lutealized symptoms such as clearly defined follicular margins and the appearance of internal echo.

Serum estradiol levels, the last pills began 4-6 days

A late post-ovulation was performed 1-3 days after ovulation to check for at least 5 progressive spermatozoa per HPF

At the end of the last clomiphene pill 3 to 4 days, elevated urinary LH levels were sufficient

Atrial administration of progesterone at least 10 ng / ml after 7-9 days of ovulation is considered sufficient.

Repeated administration: This 5-day treatment can be repeated every 30 days. In the subsequent cycle, the dose can be increased by 50 mg until ovulation is reached. Use of clomiphene for more than 6 cycles is not recommended for use by the manufacturer.

No further ultrasound is recommended to exclude any significant residual ovarian enlargement before each new treatment cycle.

Cramiphene is sometimes used to treat male hypogonadism as a substitute for testosterone replacement therapy. It has been found that in men with sexually transmitted men, testosterone levels are increased by 2-2.5 times.

Dosing Administration

Follow the instructions of the doctor to use clomiphene. Follow all directions in your prescription label. Your doctor sometimes changes your dose to ensure you get the best results. Do not use the drug in a larger or smaller amount or longer than the recommended drug.

Your doctor will undergo a medical check to ensure that you have no conditions to prevent you from safely using clomiphene.

After the first 5 days of menstruation, clomiphene usually took 5 days. Follow the doctor's instructions.

Before each treatment cycle, you need a pelvic examination. You must continue to take care of your doctor when using this medicine.

You are most likely to ovulate 5 to 10 days after taking clomiphene. In order to improve the chances of getting pregnant, you should intercourse during ovulation.

Your doctor may receive your body temperature every morning and record your daily reading on the calendar. This will help you determine when ovulation can be expected.

In most cases, clomiphene should not be used in more than three treatment cycles.

If ovulation occurs, but after three treatment cycles you are not pregnant, your doctor may stop treatment and further assess your infertility.

Store at room temperature, avoid moisture, heat and light.

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