99% Pure Trilostane Powder Pharmaceutical Raw Materials for Breast Cancer CAS13647-35-3

99% Pure Trilostane Powder Pharmaceutical Raw Materials for Breast Cancer CAS13647-35-3

99% Pure Trilostane powder Pharmaceutical raw materials for Breast Cancer CAS 13647-35-3 Whatsapp:+8618126147481 Skype:cherrysendi Emial:cherrysendi@chembj.com Trilostane Synonym: Vetoryl,Desopan, Modrastane, Modrenal, Triwinol, Win-14540 CAS Registry Number: 13647-35-3 Alias: 99% Einecs No:...

Product Details

99% Pure Trilostane powder Pharmaceutical raw materials for Breast Cancer CAS13647-35-3

Whatsapp:+8618126147481

Skype:cherrysendi

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Trilostane
Synonym: Vetoryl,Desopan, Modrastane, Modrenal, Triwinol, Win-14540
CAS Registry Number: 13647-35-3
Alias: 99%
Einecs No: 237-133-0
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Appearance: : White crystalline powder
Usage: Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.


What is rilostane

Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.


Trilostane effects

Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. including cortisol. Inhibiting this enzyme inhibits the production of cortisol. Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxy steroids dehydrogenase/delta 5,4 keto steroids isomerase, thus blocking synthesis of adrenal steroids. Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.


Trilostane COA

Tests

Specifications

Results

Identification

Positive

Confirm

Melting point

257°C to 270°C

261°C -266°C

Appearance

White to pale white solid

White solid

Heavy metals

No more than 20ppm

10ppm

Loss on drying

Not more than 0.5%

0.18%

Residue on Ignition

Not more than 0.1%

0.02%

Solubility

soluble in dimethyl sulfoxide

Conforms

soluble in pyridine

Conforms

slightly soluble in ethanol

Conforms

slightly soluble in water

Conforms

Assay (microbial)

Not less than 99.0%

99.5%

Specific Rotation

+137-139°

137.0°

Related impurities

not more than 1.0%

0.35%

HPLC purity

not less than 99.0%

99.6%

Solvent Residues

Ethanol<5000ppm

1000ppm

Conclusion

Comply with In-house standard.

Storage

Store protected from light and moisture


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112809-51-5

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84371-65-3

Methoxydienone

2322-77-2

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Estradiol valerate

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50-50-0


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2.Quality

1.Having been engaged in this field for years,before export,we are top maunfacture of steroid in China market more than ten years.

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