Male Enhancement Avanafil Powder for Treatment Erectile Dysfunction CAS330784-47-9

Male Enhancement Avanafil Powder for Treatment Erectile Dysfunction CAS330784-47-9

Male Enhancement Avanafil powder for Treatment Erectile Dysfunction CAS 330784-47-9 Whatsapp:+8618126147481 Skype:cherrysendi Emial:cherrysendi@chembj.com Avanafil CAS number: 330784-47-9 Formula: C23H26ClN7O3 Mol. mass: 483.951 g/mol Content: 99%, pharmaceutical grade Packing: 1 kg Appearance:...

Product Details

Male Enhancement Avanafil powder for Treatment Erectile Dysfunction CAS330784-47-9

Whatsapp:+8618126147481

Skype:cherrysendi

Emial:cherrysendi@chembj.com


Avanafil
CAS number: 330784-47-9

Formula: C23H26ClN7O3

Mol. mass: 483.951 g/mol

Content: 99%, pharmaceutical grade

Packing: 1 kg

Appearance: White Solid

Melting Point: 150-152°C

Storage temp.: Refrigerator

Purity: 99%+

Minimum Order Quantity: 50g

Delivery Time: 3 days

Shipping partner: DHL, UPS, TNT, FEDEX, HKEMS


Avanafil COA

Description

White or Almost White Crystalline Powder

white powder

Identification

A.B.

Positive

Assay

97.0~103.0%

99.0%

Specific Rotation

+101°~+105°

+102.6°

Loss On Drying

1.0%max

0.28%

Organic Volatile Impurities

meets the requirement.

Conforms

Related Substances

meets the requirement.

Conforms

Residual Solvents

meets the requirement.

Conforms

Particle Size

100% ≤ 20 microns

Conforms


What is Avanafil

AVANAFIL (ah VA Na fil) is used to treat erection problems in men. Avanafil belongs to the phosphodiesterase type 5 (PDE5) inhibitors drug class, a class of drugs commonly indicated for treatment of erectile dysfunction (ED).1 PDE5 inhibitors do not inhibit prostaglandins as do some agents for treating impotence (e.g., alprostadil). The safety and efficacy of avanafil was studied in three clinical trials; compared to placebo, improved erections were recorded in patients with organic and/or psychogenic ED when avanafil was administered prior to visual sexual stimulation. Avanafil is taken prior to sexual activity without regard to food. Patients with preexisting cardiovascular disease should discuss the potential cardiac risks associated with sexual activity with their healthcare professional. As with other PDE5 inhibitors, avanafil has systemic vasodilatory proprieties. In clinical evaluation, avanafil (200 mg) reduced the sitting blood pressure of healthy subjects by 8 mmHg systolic and 3.3 mmHg diastolic, with the maximum decrease observed at 1 hour after dosing. Patients with underlying cardiovascular disease could be affected adversely by such vasodilatory effects, especially in combination with sexual activity. Avanafil should not be used by men who also take nitrates because the combination can cause a sudden drop in blood pressure that can be dangerous. According to ED treatment guidelines, oral phosphodiesterase type 5 inhibitors (PDE5 inhibitor) are considered first-line therapy


Avanafil dosage

Adults: 100 mg PO once daily, approximately 15 minutes before sexual activity. The dose may be increased up to 200 mg PO, approximately 15 minutes before sexual activity or decreased to 50 mg PO, approximately 30 minutes before sexual activity, based on clinical response. Maximum dosing frequency is once daily.3 PDE5 inhibitors are first line agents for ED according to guidelines. Although associated with high rates of success, approximately 35% of ED patients fail to respond to PDE5 inhibitor therapy. A course of an alternate PDE5 inhibitor may be considered if a patient does not respond to a PDE5 inhibitor trial; a treatment failure may be deemed after at least 4 unsuccessful trials.


Avanafil benefits

The main objectives of erectile dysfunction (ED) management are to control and reduce associated organic cardiovascular risk factors and to restore the capacity to obtain and maintain a rigid penile erection.


Since oral phosphodiesterase (PDE)-5 inhibitors have a demonstrated efficiency in the number and duration of erections in patients with ED with a favourable benefit-to-risk ratio, they have been recommended in European guidelines as the first-line medical therapy for ED.


Avanafil COA


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Other Sex enhancement hormone we offer

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Packing&shipping

1.Packages are generally dispatched within 24 hours after payment

2.After shipping we will provide: tracking number;pictures with your parcel;

3.Shipping Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.

4.Air transport for large quantity

5.Shipping time:Most countries can arrived within 3-10 days door to door


More information please feel free conatct me

Whatsapp:+8618126147481

Skype:cherrysendi

Emial:cherrysendi@chembj.com

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